database
channelopathy
channelopathy
channelopathy
channelopathy
channelopathy
channelopathy
channelopathy
channelopathy
channelopathy
channelopathy
The Channelopathy Database: ChannelopathyDB

Knowledge Gap: As it is usual with rare diseases, respective patients often complain about a long-lasting doctor's odyssey. This is due to the current severe lack of validated information. This is needed to support clinical management, diagnostics and consequently doctor's decision making. Ion Channel diseases are particularly underserved. Today's ion channel databases do clearly not fulfil this need - they are incomplete, narrowly focussed, fragmented and oriented towards different research and healthcare fields. Without this ultimate initial step our enemy stays invisible and it will keep us away from finding helpful therapies. See below!

Patient Benefit: Before a rationale therapeutic strategy can be designed it is essential to know in detail the genetic causes responsible for a specific clinical state. Thus, the establishment of a structured catalogue of the reported genetic variants has first priority. The below quotation may sound provocative. The CHFO does not understand the claim in a general routine. But, when living with hereditary disorders, it can make sense. Recently, the mutated SPTL1 and SPTL2 genes have been discovered as biological cause of the HSAN1 disorder. This knowledge ALONE allowed an immediate cure: Simple serine intake.

3X Knowing: "Knowing our genes helps knowing our enemy and knowing our therapy".
The Channelopathy Database discloses comprehensive information about ion channel diseases for scientists, doctors and patients.